Query String: CERITINIB
LDK378 US10618884, Example 16 CERITINIB CHEMBL2403108 US10053458, Comparative Example 2 US9809572, Example 16 BDBM50436850
- ChEMBL_1880814 (CHEMBL4382313) Inhibition of EGFR in human DFCI032 cells assessed as reduction in cell viability after 72 hrs in presence of ceritinib by MTS assay
- ChEMBL_1880818 (CHEMBL4382317) Inhibition of EGFR in human DFCI076 cells assessed as reduction in cell viability after 72 hrs by MTS assay in presence of ceritinib
- ChEMBL_2216387 (CHEMBL5129519) Inhibition of N-terminal GST-tagged human ceritinib-resistant ALK L1196M mutant (1058 to 1620 residues) cytoplasmic domain expressed in baculovirus infected Sf21 cells incubated for 1 hrs in the presence of ATP by mobility shift assay
- ChEMBL_2216393 (CHEMBL5129525) Inhibition of N-terminal GST-tagged human ceritinib-resistant ALK G1202R mutant (1058 to 1620 residues) cytoplasmic domain expressed in baculovirus infected Sf21 cells incubated for 1 hrs in the presence of ATP by mobility shift assay